About MitoWeb

Description

MitoWeb is a platform for distributing mitochondrial information and developing web-based bioinformatics tools for its analysis. Core components currently include MITOMAP, a curated repository of data and the MITOMASTER analysis framework (available for Chrome & Firefox users). Your feedback is appreciated. Please direct correspondence to the Mitomap Team.

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Brief History

In 1996 Dr. Doug Wallace was head of the Center for Molecular Medicine at Emory University, and Marie Lott was the lab manager. In a collaborative effort, Andy Kogelnik, a graduate student at Georgia Tech working under Dr. Shamkant Navathe, developed MITOMAP as part of the dissertation work for his PhD. Marie has served as curator of the variation data since its beginning, and has generated many other pages of information that are of interest to the mitochondrial community. Several graduate students made amendments to the programming of MITOMAP in 1998 and 1999.

The MITOMAP programs were rewritten by Marty Brandon in 1999 and the data was ported into Oracle, and later into PostgresSQL. In 2002, the center moved to UC-Irvine and was renamed MAMMAG. MITOMAP moved again in 2010 to the Children's Hospital of Philadelphia as part of Doug Wallace's newly created Center for Mitochondrial and Epigenomic Medicine. The long-term goal of the MITOMAP/MitoWeb endeavor has been to create an open resource for the analysis of mitochondrial data and to utilize community contribution to collect data and develop new applications.

The MITOMAP database and MITOMASTER tools are being completely upgraded for 2013 by Jeremy Leipzig and Michael Xie of the Center for Biomedical Informatics at the Children's Hospital of Philadelphia. Marie Lott (Atlanta, GA) continues as data curator and relies heavily on the expertise of Olga Derbeneva (Philadelphia, PA) and Vincent Procaccio (Angers, France). MITOMAP has also recently welcomed a new data collaboration with Mannis van Oven (Rotterdam, Netherlands) of Phylotree.

A big thanks also goes to the following contributors for their past help with the creation and development of MITOMAP: J. C. Perin, M. Sarmady, P. F. Baldi, J. Poole, J. Kreuziger, E. Ruiz-Pesini, M. D. Brown, A. M. Kogelnik, K. Kladitis, G. C. Katdare, S. B. Navathe, S. Spolim, A. Torroni, K. Huoponen