Conservation denotes the percentage of residues that match that of the rCRS among selected species. A query variant is depicted in isolation (i.e., other variants in a test sequence are not shown) and is flanked by rCRS reference for clarity.
| Species | -5 | -4 | -3 | -2 | -1 | 0 | +1 | +2 | +3 | +4 | +5 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Variant at rCRS pos 10086 (locus pos 10) of ND3 | L | I | L | M | I | D | T | L | L | A | L |
| Homo sapiens (rCRS) | L | I | L | M | I | N | T | L | L | A | L |
| Alligator mississippiensis | I | M | L | T | M | S | S | I | T | V | S |
| Artibeus jamaicensis | I | T | L | L | T | N | T | F | L | A | S |
| Balaenoptera musculus | L | T | L | L | T | N | T | T | L | A | L |
| Balaenoptera physalus | L | T | L | L | T | N | T | T | L | A | L |
| Bos taurus | L | A | L | L | T | N | F | T | L | A | T |
| Canis lupus familiaris | L | T | L | M | T | N | V | T | L | A | S |
| Cebus albifrons | L | T | L | A | T | S | T | L | L | A | L |
| Ceratotherium simum | L | T | L | F | I | N | T | S | L | A | S |
| Cyprinus carpio | T | I | L | T | I | T | V | A | L | S | L |
| Dasypus novemcinctus | I | T | L | F | I | N | M | S | L | A | S |
| Didelphis virginiana | I | T | L | I | T | N | S | L | L | S | T |
| Drosophila melanogaster | F | I | A | L | L | I | L | L | I | T | T |
| Equus asinus | L | T | L | L | T | N | T | L | L | A | S |
| Equus caballus | L | T | L | L | T | N | T | L | L | A | S |
| Erinaceus europaeus | I | M | I | F | T | N | T | T | L | A | I |
| Felis catus | L | A | L | L | T | N | T | L | L | S | T |
| Gallus gallus | F | M | L | S | L | S | F | L | L | S | A |
| Glis glis | L | T | I | F | I | N | L | T | L | S | S |
| Gorilla gorilla | L | I | L | M | T | N | T | L | L | A | L |
| Halichoerus grypus | L | T | L | F | T | N | T | A | L | A | S |
| Hippopotamus amphibius | M | A | L | L | T | N | T | A | L | A | S |
| Hylobates lar | L | A | L | M | I | N | T | L | L | A | L |
| Loxodonta africana | I | T | L | L | T | N | T | M | L | T | S |
| Macaca sylvanus | L | A | L | M | T | N | T | L | L | T | S |
| Macropus robustus | I | T | L | I | I | N | T | A | L | S | T |
| Mus musculus | T | V | I | F | I | N | I | L | L | S | L |
| Nycticebus coucang | I | M | L | I | T | N | T | S | L | A | S |
| Ornithorhynchus anatinus | I | A | L | L | I | N | T | G | L | A | T |
| Oryctolagus cuniculus | L | V | L | L | I | N | T | T | I | S | L |
| Ovis aries | I | T | L | L | T | N | F | T | L | A | T |
| Pan paniscus | L | I | L | M | T | N | T | L | L | A | L |
| Pan troglodytes | L | I | L | M | T | N | T | L | L | A | L |
| Papio hamadryas | L | A | L | T | V | N | T | L | L | T | A |
| Phoca vitulina | L | T | L | F | T | N | T | A | L | A | S |
| Pongo abelii | L | A | L | T | V | N | T | L | L | A | L |
| Pongo pygmaeus | L | A | L | T | I | N | T | L | L | A | L |
| Rattus norvegicus | I | I | I | T | I | N | I | T | L | S | F |
| Rhinoceros unicornis | L | T | L | L | I | N | T | L | L | S | S |
| Sciurus vulgaris | I | T | L | L | I | N | I | S | I | S | L |
| Sus scrofa | L | T | L | L | T | N | V | T | L | A | S |
| Talpa europaea | L | T | I | T | V | N | T | L | L | S | S |
| Tarsius bancanus | M | S | L | I | T | N | M | A | L | A | L |
| Vicugna pacos | L | A | L | L | T | N | T | T | L | A | S |
| Xenopus laevis | T | I | L | M | I | A | M | T | L | S | T |