Conservation denotes the percentage of residues that match that of the rCRS among selected species. A query variant is depicted in isolation (i.e., other variants in a test sequence are not shown) and is flanked by rCRS reference for clarity.
| Species | -5 | -4 | -3 | -2 | -1 | 0 | +1 | +2 | +3 | +4 | +5 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Variant at rCRS pos 14463 (locus pos 71) of ND6 (light strand) | V | F | G | Y | T | A | A | M | A | I | E |
| Homo sapiens (rCRS) | V | F | G | Y | T | T | A | M | A | I | E |
| Alligator mississippiensis | V | F | A | F | C | V | G | F | T | D | D |
| Artibeus jamaicensis | V | F | G | Y | T | T | A | M | A | T | E |
| Balaenoptera musculus | V | F | G | Y | T | T | A | M | A | T | E |
| Balaenoptera physalus | V | F | G | Y | T | T | A | M | A | T | E |
| Bos taurus | V | F | G | Y | T | T | A | M | A | T | E |
| Canis lupus familiaris | V | F | G | Y | T | T | A | M | A | T | E |
| Cebus albifrons | V | F | G | Y | T | A | A | M | A | V | D |
| Ceratotherium simum | V | F | G | Y | T | T | A | M | A | T | E |
| Cyprinus carpio | V | F | A | Y | A | A | - | L | A | A | E |
| Dasypus novemcinctus | V | F | G | Y | T | T | A | M | A | T | E |
| Didelphis virginiana | V | F | G | Y | T | T | A | M | A | T | E |
| Drosophila melanogaster | L | F | I | Y | V | T | S | L | A | S | N |
| Equus asinus | V | F | G | Y | T | T | A | M | A | T | E |
| Equus caballus | V | F | G | Y | T | T | A | M | A | T | E |
| Erinaceus europaeus | V | F | G | Y | T | A | A | M | A | M | E |
| Felis catus | V | F | G | Y | T | T | A | M | A | T | E |
| Gallus gallus | V | F | V | Y | S | V | S | L | A | A | D |
| Glis glis | V | F | G | Y | T | T | A | M | A | T | E |
| Gorilla gorilla | V | F | G | Y | T | T | A | M | A | I | G |
| Halichoerus grypus | V | F | G | Y | T | T | A | M | A | T | E |
| Hippopotamus amphibius | V | F | G | Y | T | T | A | M | A | T | E |
| Hylobates lar | V | F | G | Y | T | T | A | M | A | I | E |
| Loxodonta africana | V | F | G | Y | T | I | A | M | A | T | E |
| Macaca sylvanus | V | F | G | Y | T | M | A | M | A | I | E |
| Macropus robustus | V | F | G | Y | T | A | A | M | A | T | E |
| Mus musculus | V | F | G | Y | T | T | A | M | A | T | E |
| Nycticebus coucang | V | F | G | Y | T | T | A | M | A | T | E |
| Ornithorhynchus anatinus | V | F | G | Y | T | A | A | M | A | T | E |
| Oryctolagus cuniculus | V | F | G | Y | T | T | A | M | A | T | E |
| Ovis aries | V | F | G | Y | T | T | A | M | A | T | E |
| Pan paniscus | V | F | G | Y | T | T | A | M | A | I | E |
| Pan troglodytes | V | F | G | Y | T | T | A | M | A | I | E |
| Papio hamadryas | V | F | G | Y | T | A | A | M | A | I | E |
| Phoca vitulina | V | F | G | Y | T | T | A | M | A | I | E |
| Pongo abelii | V | F | G | Y | T | T | A | M | A | I | E |
| Pongo pygmaeus | V | F | G | Y | T | T | A | M | A | I | E |
| Rattus norvegicus | V | F | G | Y | T | T | A | M | A | T | E |
| Rhinoceros unicornis | V | F | G | Y | T | T | A | M | A | T | E |
| Sciurus vulgaris | V | F | G | Y | T | T | A | M | A | T | E |
| Sus scrofa | V | F | G | Y | T | T | A | M | A | T | E |
| Talpa europaea | V | F | G | Y | T | T | A | M | A | M | E |
| Tarsius bancanus | V | F | G | Y | T | T | A | M | A | M | E |
| Vicugna pacos | V | F | G | Y | T | T | A | M | P | T | E |
| Xenopus laevis | V | F | A | Y | S | A | - | A | R | A | K |