MITOMAP: Reported Multiple mtDNA Deletions Within Individuals

Last Edited: May 25, 2012

Deletion Junction (nt:nt)	Deletion Size(bp)	Repeat Type	Repeat Location	Patient ID	References

"5786:13923","-8136","D, 4/4","5785-5788/13918-13921","22","1""5787:13920","-8132","D, 4/4","5785-5788/13918-13921","22","1""7469:16071","-8601","D, 4/4","7469-7472/16071-16074","26","1""7818:16071","-8252","D, 6/6","7819-7824/16071-16076","26","1""7819:16070","-8250","D, 6/6","7819-7824/16071-16076","26","1""7869:16075","-8205","D, 7/7","7872-7878/16072-16078","26","1""7920:16078","-8157","D, 4/4","7915-7918/16068-16071","26","1""7922:16074","-8151","D, 4/4","7919-7922/16065-16068","26","1""7989:16071","-8081","D, 5/5","7986-7990/16065-16069","26","1""7991:16070","-8078","D, 5/5","7986-7990/16065-16069","26","1""7817:16071","-8253","D, 6/6","7819-7824/16071-16076","27","1""7819:16071","-8251","D, 6/6","7820-7825/16071-16076","27","1""7919:16070","-8150","D, 4/4","7915-7918/16069-16072","27","1""7989:16071","-8081","D, 5/5","7986-8990/16065-16069","27","1""7990:16068","-8077","D, 5/5","7986-7990/16065-16069","27","1""8029:16071","-8041","D, 6/7","8030-8036/16071-16076","27","1""8030:16071","-8040","D, 6/7","8030-8036/16071-16076","27","1""8030:16070","-8039","D, 6/7","8030-8036/16071-16076","52","1""8636:16073","-7436","D, 12/12","8637-8648/16073-16084","52","1""7914:16070","-8155","D, 4/4","7915-7918/16069-16072","53","1""8254:16070","-7815","D, 3/3","8252-8254/16071-16073","53","1""9281:13810","-4528","D, 8/8","9274-9281/13801-13808","12","1""9440:14083","-4642","D, 10/10","9431-9440/14072-14081","12","1""9444:13964","-4519","D, 8/8","9437-9444/13955-13962","12","1""9497:13735","-4237","D, 12/12","9486-9497/13722-13733","12","1""9532:14135","-4602","D, 7/7","9526-9532/14127-14133","12","1""9574:13951","-4376","D, 4/4","9571-9574/13946-13949","12","1""9587:13953","-4366","D, 9/9","9579-9587/13943-13951","12","1""9600:14138","-4537","D, 5/5","9596-9600/14132-14136","12","1""9609:14147","-4537","D, 5/5","9606-9610/14141-14145","12","1""10758:14138","-3379","D, 8/8","10151-10758/14128-14136","12","1""10925:14152","-3226","D, 5/5","10921-10925/14146-14150","12","1""13761:14252","-490","D, 8/8","13754-13761/14243-14250","12","1""7899:15642","-7742","D, 4/4","7905-7908/15646-15649","1-III-8","1""7920:16071","-8150","D, 4/4","7919-7922/16065-16068","2-III-3","1""9079:15312","-6232","D, 5/5","9075-9079/15307-15311","2-IV-5","1""7794:16072","-8277","D, 6/6","7794-7799/16072-16077","3-II-5","1""9193:15322","-6128","D, 6/7","9189-9194/15319-15325","3-III-9","1""547:4443","-3895","D, 13/13","536-548/4430-4442","AD-PEO 1-3","1""8469:13447","-4977","D, 13/13","8470-8482/13447-13459","AD-PEO 1-3, AR-PEO 1-3","1""9844:16064","-6219","D, 9/10","9833-9844/16061-16070","II-5","1""9966:15801","-5834","D, 4/5","9952-9956/15798-15802","II-5","1""7619:15032","-7412","D, 4,4","7620-7623/15032-15035","III-1","1""7845:15761","-7915","D, 4/4","7841-7845/15751-15753","III-1","1""7931:15761","-7829","D, 7/8","7924-7931/15760-15767","III-1","1""7775:13532","-5756","D, 7/7","7769-7775/13525-13531","Proband-Aged","1""7959:13787","-5827","D, 6/6","7954-7959/13781-13786","Proband-Aged","1""7992:15730","-7737","D, 7/7","7986-7992/15723-15729","Proband-Aged","1""8030:16075","-8044","D, 5/5","8030-8034/16071-16075","Proband-Aged","1""8034:16076","-8041","D, 5/5","8030-8034/16071-16075","Proband-Aged","1""8213:16070","-7856","D, 6/6","8207-8212/16071-16076","Proband-Aged","1""8439:16075","-7635","D, 7/7","8433-8439/16068-16074","Proband-Aged","1""8476:14812","-6335","D, 7/7","8470-8476/14805-14811","Proband-Aged","1""8482:13460","-4977","D, 13/13","8470-8482/13447-13459","Proband-Aged","1""8648:16085","-7436","D, 12/12","8637-8648/16073-16084","Proband-Aged","1""8387:16071","-7683","NR",".","Proband-Chronic Fatigue","1""8612:16072","-7459","NR",".","Proband-Chronic Fatigue","1""8631:13513","-4881","D, 7/7","8625-8631/13506-13512","Proband-Chronic Fatigue","1""9591:13052","-3460","D, 6/6","9546-9591/13046-13051","Proband-MD","1""6341:14005","-7663","D, 11/11","Not Reported","Proband-MNGIE","1""11480:16071","-4591","D, 3/4","Not Reported","Proband-MNGIE","1""8316:15802","-7485","NR",".","Proband-UV","1""8344:15633","-7288","NR",".","Proband-UV","1""8553:15585","-7031","NR",".","Proband-UV","1""8580:15731","-7150","D, 7/7","8581-8587/15731-15737","Proband-UV","1""7967:11312","-3344","D, 5/5","7968-7972/11312-11316","Sib1, Sib2","1""8727:13698","-4970","D, 6/6","8712-8717/13688-13693","Sib1, Sib2, Mother","1""8774:13990","-5215","D, 6/6","8772-8777/14001-14006","Sib1, Sib2, Mother","1""8931:13766","-4834","D, 6/6","8931-8936/13768-13773","Sib1, Sib2, Mother","1""7474-7479:11435-11440","-3960","D, 5/5","7475-7479/11435-11439","Subject 01 Fiber 01","1""11514:13810","-2295","NR",".","Subject 01 Fiber 02","1""11739:15572","-3832","NR",".","Subject 01 Fiber 03","1""6862:13061","-6198","NR",".","Subject 01 Fiber 04","1""5787:13924","-8136","NR",".","Subject 01 Fiber 05","1""6330-6341:13994-14005","-7663","D, 16/17","6325-6341/13989-14004","Subject 01 Fiber 06","1""5787:15576","-9788","NR",".","Subject 01 Fiber 07","1""9799:15557","-5757","NR",".","Subject 02 Fiber 08","1""9921:16071","-6149","NR",".","Subject 02 Fiber 09","1""6429:14101","-7671","NR",".","Subject 02 Fiber 10","1""9665:15183","-5517","NR",".","Subject 02 Fiber 11","1""8568-8576:13954-13962","-5385","D, 8/8","8569-8576/13954-13961","Subject 02 Fiber 12","1""7181:14565","-7383","I, 4/4","7182-7185/14565-14568","Subject 06 Fiber 13","1""9242-9246:13054-13058","-3811","D, 4/4","9243-9246/13054-13057","Subject 06 Fiber 14","1""7723:14110","-6386","NR",".","Subject 06 Fiber 15","1""7175-7185:14110-14120","-6934","D, 10/10","7176-7185/14110-14119","Subject 06 Fiber 16","1""9766-9773:13749-13756","-3982","D, 7/7","9767-9773/13749-13755","Subject 06 Fiber 17","1""4881:16067","-11185","NR",".","Subject 06 Fiber 18","1""6330-6340:13994-14005","-7663","D, 16/17","6325-6341/13989-14004","Subject 06 Fiber 19","1""10934-10939:15525-15530","-4590","D, 5/5","10935-10939/15525-15529","Subject 06 Fiber 20","1""7402:13677","-6274","NR",".","Subject 06 Fiber 21","1""9346-9351:13149-13154","-3802","D, 7/8","9344-9351/13146-13153","Subject 06 Fiber 22","1""7404-7407:12393-12396","-4988","D, 10/11","7397-7407/12385-12395","Subject 06 Fiber 23","1""9578-9587:13944-13953","-4365","D, 9/9","9579-9587/13944-13952","Subject 06 Fiber 24","1""9251-9258:14422-14429","-5170","D, 7/7","9252-9258/14422-14428","Subject 09 Fiber 25","1""8466-8475:14372-14381","-5905","D, 9/9","8467-8475/14372-14380","Subject 09 Fiber 26","1""12079-12084:15849-15854","-3769","D, 5/5","12080-12084/15849-15853","Subject 09 Fiber 27","1""7407-7414:14561-14568","-7153","D, 12/13","7402-7414/14555-14567","Subject 09 Fiber 28","1""16157-16164:16312-16319","-154","D, 7/7","16158-16164/16312-16318","Subject 09 Fiber 29","1""6330-6341:13994-14005","-7663","D, 16/17","6325-6341/13989-14004","Subject 09 Fiber 30","1""7850:13474","-5623","NR",".","Subject 09 Fiber 31","1""8555-8561:13979-13985","-5429","D, 6/6","8556-8561/13979-13984","Subject 09 Fiber 32","1""6936-6940:15447-15451","-8510","D, 7/8","6933-6940/15444-15450","Subject 10 Fiber 33","1""6522-6527:15050-15055","-8527","D, 8/9","6523-6531/15050-15058","Subject 10 Fiber 34","1""10493-10497:14756-14760","-4262","D, 4/4","10494-10497/14756-14759","Subject 10 Fiber 35","1""6330-6341:13994-14005","-7663","D, 16/17","6325-6341/13989-14004","Subject 10 Fiber 36, 37","1""6936-6940:15447-15451","-8510","D, 4/4","6937-6940/15447-15450","Subject 10 Fiber 38, 39","1""3263:16071","-12807","NR",".","Subject 10 Fiber 40","1""10977-10984:15536-15543","-4557","D, 7/7","10978-10984/15536-15542","Subject 11 Fiber 41","1""7857:12283","-4425","NR",".","Subject 11 Fiber 42","1""11056-11065:15851-15860","-4794","D, 9/9","11057-11065/15851-15859","Subject 11 Fiber 43","1""10977-10984:15536-15543","-4558","D, 7/7","10978-10984/15536-15542","Subject 11 Fiber 44","1""10936-10940:15542-15546","-4605","D, 4/4","10937-10940/15542-15545","Subject 11 Fiber 45","1""5789:16075","-10285","NR",".","Subject 11 Fiber 46","1""5785:16072","-10286","NR",".","Subject 11 Fiber 47","1""7098:16072","-8973","NR",".","Subject 11 Fiber 48","1"

Note:

Only deletions with sequenced breakpoints are included. Reported deletion junctions may be approximate due to the presence identical repeat sequences at the break points. Alternate junctions may be reported in the cited literature due to the inherent ambiguities of the direct repeats. Other reports of multiple deletions mapped within an individual have been published without specific sequence data for the deletion breakpoints.

• D = direct repeat;
• I = indirect repeat, homology as specified;
• Patient ID # = identification number of specific individual examined in cited work.