MITOMAP: Polymorphic MtDNA Low Resolution Restriction Sites

Detected by Low Resolution Screening of Human Populations

This page is no longer maintained.

Last Edited: Jun 01, 2003

Enzyme	Cut Sequence	Low Resolution Restriction Sites	References
1Bgl I	GCCNNNNNGGC	~	references
1BstEII	GGTNACC	+184	references
1BstNI	CCRGG	+319,-8991,+10094,-13704,+15045,+15728,+16502	references
1BstXI	CCANNNNNNTGG	~	references
1Dde I	CTNAG	+15754	references
1Dra I	TTTAAA	~	references
1EcoRI	GAATTC	-4121	references
1EcoRV	GATATC	+16274	references
1Fnu4HI	GCNGC	+260,-13708	references
1FnuDII	CGCG	+13939	references
2Hae II	PGCGCQ	+1300,-4529,+4830,+8268,+8988,+8991,-9052,+9250,+9266,+9689,+9700,+11001,-13594,-14858,+15552	references
2Hae III	GGCC	+576,+663,-1463,+1515,+3090,-3315,+3391,-3427,-3607,+4092,+4793,-4848,-5261,-6260,+6333,+6425,+7041,+7976,-8250,-8391,-8572,-8994,-9438,+10097,+10289,-13702,+13803,+14279,+14749,-15047,-15152,-15172,+15431,+16254,+16398,+16517,+16534	references
2Hha I	GCGC	+255,+4831,-7598,+7828,+8858,-9053,-9380,+9400,+12501,-13595,+13940	references
2HincII	GTQPAC	-1004,+1106,-5917,-7853,+8638,+12114,-12406,-13259,-13634,+16062,+16200	references
2HindIII	AAGCTT	+4582,+9736	references
2HinfI	GANTC	-4360,+7902,+8750,-8783,+9376,+12192,+13605,-14976,-15234,-15723,+16389	references
2Hpa I	GTTAAC	+1004,+3592,+12026,+12114,-12406	references
2HphI	GGTGA	+184	references
2Kpn I	GGTACC	-16129,+16133	references
2Mae I	CTAG	+4914	references
3Mbo I	GATC	+8,-7859,+8565,-8592,+13116,+16215,+16398	references
3Mnl I	CCTC	-144,+16185,-16187,-16222,+16355	references
3Msp I	CCGG	-104,+496,-931,+4241,-4711,-5742,+7977,-8112,-8150,+8646,+11170,+11436,+11454,-12123,+12813,+13070,+13100,+13496,-13712,+14205,+15485,+15503,+15510,-15925,-16453	references
3Nci I	CCSGG	-13364	references
3Nco I	CCATGG	+6900	references
3Nde I	CATATG	~	references
3Nla III	CATG	+4216	references
3Pst I	CTGCAG	+7364,+16200	references
3Pvu II	CAGCTG	+981,+12751	references
3Rsa I	GTAC	-1307,+1315,+2120,-3337,+4621,+5009,+8356,-8998,+15282,-15812,+15949,-16049,-16096,-16208,-16303,-16310	references
4Sac I	GAGCTC	-9643	references
4Sau96I	GGNCC	+16516	references
4Sca I	AGTACT	+4740,-9745	references
4Ssp I	AATATT	~	references
4Stu I	AGGCCT	+7196,-13701,-15046	references
4Taq I	TCGA	+7214,+8022,+10084,-10180,-11421,+14158,+16217,+16278	references
4Xba I	TCTAGA	-7440,-10256	references
4Xho I	CTCGAG	+9736,+12500,+14157	references
Acc I	GTVWAC	+13635,+14550,-15254	references
Alu I	AGCT	+8678,-14015,-14304	references
Apa I	GGGCCC	-8249	references
Ava I	CQCGPG	~	references
Ava II	GGRCC	+1830,+3876,+4280,+4308,+4346,+4432,+4776,+4811,+5229,+5260,+6000,+6324,+6382,+6700,+7804,+8229,+8249,+8270,+8391,+8400,+12130,+12191,-12629,-13367,+14258,+14400,+14900,+15487,+15490,+15499,+15882,+15890,-16390,+16503	references
BamHI	GGATCC	+13366,-14258,+16389,+16491	references
Ban I	GGQPCC	+4632	references
Ban II	GPGCQC	-8249	references
Bcl I	TGATCA	+6459,-7657,-8591,+14221,+16144,+16397	references

Note:

These sites have been assigned either by restriction analysis of the entire mtDNA and Southern blots and are accurate to varying degrees, or by restrictioin analysis of short portions of the mtDNA. Restriction sites separated by a slash indicate that the mutation could have occured in one or the other of the listed sites. The symbol "~" indicates that the site gain is somewhere near the indicated nucleotide position. Each nucleotide listed is the first nucleotide of the restriction endonuclease recognition sequence, Genbank NC_012920. Codes for recognition sites are: N=A/G/C/T; P=A/G; Q=C/T; S=C/G; W=G/T; V=A/C. Some references were not included because polymorphic sites were not mapped.